High cholesterol

About high cholesterol

Cholesterol has an important role in the way your body works. Your body needs cholesterol to:

• make hormones and vitamin D
• make bile acids, which help your gut to digest the food you eat
• construct the outer layer (membrane) of your body’s cells

But if you have a high level of certain types of cholesterol, you increase your risk of cardiovascular disease – for example,  and . This is because one type of cholesterol can cause fatty deposits (known as plaques) to build up inside your arteries. Over time, these can make your arteries narrower and narrower, which restricts the flow of blood to organs such as your heart. This can affect other parts of your body too, including your arms and legs ().

There’s plenty you can do to manage cholesterol and keep it at healthy levels.

Types of cholesterol

A protein in your blood carries cholesterol around your body. This combination of fat and protein is called a lipoprotein. There are different types of lipoprotein, and they may be harmful or beneficial to your health. This is why you may have heard about ‘good’ cholesterol and ‘bad’ cholesterol. 

Good cholesterol

High-density lipoprotein (HDL) helps to get rid of excess cholesterol by carrying it from your tissues to your liver. Your liver then breaks down the cholesterol so your body can get rid of it. Your liver uses it to make bile that helps with digestion, and some of this is removed from the body as a waste product in your poo.

Having lots of HDL in your blood is a good thing – it helps to prevent heart disease, so it’s called ‘good’ cholesterol.

Bad cholesterol

Low-density lipoprotein (LDL) carries cholesterol from your liver to the cells around your body where it’s needed. But if the level of LDL in your blood is too high, it can cause fatty deposits to build up in your blood vessels (atherosclerosis). This can increase your risk of heart disease and stroke, so LDL is called ‘bad’ cholesterol. 

However, although LDL is the main ‘bad’ cholesterol, there are some other types which can also be harmful. That’s why doctors now often talk about non-HDL cholesterol as the ‘bad’ cholesterol. Non-HDL cholesterol is ‘all the cholesterol in your blood which isn’t good cholesterol’.

Causes of high cholesterol

High cholesterol is often caused by a number of things, which all act to increase your cholesterol level. As well as your genetic makeup, these may include:

• a diet that’s high in saturated fat or trans fats
• not doing much exercise
• being overweight or obese
• drinking too much alcohol

Sometimes, high cholesterol is caused by a condition that runs in your family called familial hypercholesterolaemia. This means you may have a very high cholesterol level, even if you have a healthy lifestyle.

Other health conditions may cause high cholesterol. These include:

• poorly controlled
• certain kidney and liver diseases
• an 

Some medicines can raise your cholesterol. These include:

• oral contraceptives
• steroids

Symptoms of high cholesterol

Diagnosis of high cholesterol

Measuring cholesterol

Your doctor can measure your cholesterol levels with a blood test. The test measures the different types of cholesterol and the total amount of cholesterol in your blood. It may also measure another type of fat called triglycerides. A high level of triglycerides is also a risk factor for heart disease and stroke.

Your doctor surgery will tell you how to prepare for the test. They may ask you not to eat anything for about 12 hours before having the blood test. Always follow any instructions your doctor or doctor  surgery gives you. 

It’s important for everyone to aim for healthy blood cholesterol levels. This means a: 

• low total cholesterol
• low level of LDL cholesterol
• high level of HDL cholesterol

Here is a general guide to cholesterol levels in healthy adults:

• total cholesterol (TC): 5mmol/L or below
• non-HDL (all ‘bad’) cholesterol: 4mmol/L or below
• LDL (main ‘bad’) cholesterol: 3mmol/L or below
• HDL (‘good’) cholesterol: 1mmol/L or above
• cholesterol ratio TC/HDL: 4mmol/L or below
• triglycerides: 2.3mmol/L or below

These figures only give a general idea of normal cholesterol levels. It’s important to discuss with your doctor or nurse what your test results mean for you individually. They’ll take into account other factors, such as your age, sex, body mass index (BMI), blood pressure, family history and if you smoke. They’ll also consider other health conditions you may have or medicines that you take.

Levels of cholesterol in your blood can vary from day to day. So, your doctor may want to repeat the test before they recommend any treatment. 

Who should have a cholesterol test?

When you reach 40, your  doctor may offer you a cholesterol test. This will be part of a health check that you have every five years to work out your risk of developing heart disease and stroke.

Your doctor may also offer you a cholesterol test if you:

• have a
• have
• are overweight or
• have a family history of high cholesterol (known as familial hypercholesterolaemia)
• have heart disease
• smoke
• are unable to get or maintain an erection (erectile dysfunction)

Self-help for high cholesterol

To begin with, your doctor will recommend some lifestyle changes you can make to reduce your risk of heart attack and stroke. These may include the following.

• . If you smoke, you have less good cholesterol in your bloodstream. If you quit, you can help to keep your cholesterol levels healthy and improve your health.
• There isn’t a high cholesterol diet as such but do take steps to reduce fat in your diet, particularly saturated and trans fats. Try to replace saturated and trans fats with unsaturated fats where you can.
• Make other – eat more fibre and more wholegrain carbohydrate foods because this can help to lower LDL cholesterol. And eat more fruit and vegetables, oats, beans and pulses (for example, lentils and soya).
• Exercise more. If you’re physically active, it can help to keep your cholesterol levels healthy.
•  to help to reduce your LDL cholesterol level. Aim to be a healthy weight and you’ll feel the benefit.
• Don’t drink more than the recommended limits.

Some foods have quite a lot of cholesterol in them. , experts think that it’s much more important to reduce the amount of saturated fats  you eat, and to cut out trans fats. If you eat a lot of saturated and trans fat, it increases how much cholesterol your liver produces, and slows down how quickly it’s removed from your body. But do cut down on the high cholesterol foods if your doctor or dietitian advises you to.

If you add plant stanols and sterols to your diet, it may help keep your cholesterol levels healthy. These are found in fruits, vegetables, nuts and wholegrains. They’re also added to some food and drink, such as mini-drinks, yogurts and spreads.

Treatment of high cholesterol

The main group of medicines for high cholesterol are called . Your doctor may recommend you take a statin if you have made changes to your lifestyle but they haven’t reduced your cholesterol level enough. Or they may recommend them from the start if you have a risk of problems like heart disease.

It’s your choice whether or not you take statins. To help you to make a decision, your doctor will discuss their risks and benefits with you before you start any treatment.

Your doctor will usually ask to check your cholesterol level again around three months after you’ve started treatment, to see how well it’s working. If you don’t get on with your treatment, or it’s not working very well, your doctor may suggest you change the dose or try a different statin. They may recommend alternative medicines or seek specialist advice if you find you can’t tolerate statins even after trying three different kinds.

You shouldn’t take statins if you’re pregnant. And if you plan to get pregnant, stop taking statins three months before you start trying. Ask your doctor for more information.

Prevention of high cholesterol

High cholesterol is often preventable if you make changes to your lifestyle and diet. See our self-help section for information on how to make these healthy changes. You can also find some tips on maintaining healthy cholesterol levels.

This video also explains how to keep your heart healthy.